Like the {colored} Prism Goggles, you have to turn on Enable Post Effects.
Options -- Display -- [Advanced] -- [X] Enable Post Effects.
The effect goes in the Buffs window with no timer, it's Permanent.
With Post Effects on it slowed me down a little. Everything you see turns into a negative image,
The UI stays normal, however, so chat boxes and most F10 toggled windows are not affected.
Don't know where this would come in useful, unless Sony added a monster that distorts your vision
and these goggles counteract it... For now it's a toy.