Any of the classes that can use those and for whom it would be an upgrade should be able to bid or roll on this.
45/40 with 40AC, +10 DEX/AGL +75HP... that is exceptional... about the only class listed that would be likely to pass on this is Berserker as their epic is better and if they are doing this mob, they ought to have their epic.
For a Ranger, this is a great 2HS. Most rangers do not invest heavily in 2H slashers as they put their earnings into bows and 1H smacky/pokey/slashies toys. But when a ranger starts racking up the aa's into the hundreds, 2HS is again a very feasible weapon choice. The 40AC is of great benefit to a ranger as it is pretty difficult to get near the ac cap on a chain class. Yes the +15 int is a waste on a ranger, but nothing else about the weapon is.
Shadowknights and Paladins get a vast number of choices of some exception 2HS/2HP weapons with similar stats and ratio to this. Epic Berserks would have zero need for this. Frankly, the greatest benefit from this weapon would be garnered by a ranger or warrior and if it went to a ranger, it would likely be the only 2HS carried by that toon until hitting the higher elemental planes, higher tier GoD zones, or Time.
Most SK's would love this weapon, until they got a better one, which for SK or Pally, isn't that difficult.
So to sum up, if you are part of a raid that can win this nice slasher, and you can and will use it, bid or roll on it. It frankly isn't suited especially to any one of the classes that can use it. Few tradeable multiclass items are really suited solely to just one of the classes listed on them.